Lyme Biowarfare Interview
Interview
With Willy Burgdorfer
Wednesday, June 10, 2009
It
has been told by some that Willy Burgdorfer, the
discoverer of the Lyme disease spirochete, said
that he was recruited from Austria to work in the U.S with biowarfare.
The following interview can be found at
underourskin.com Blog
Lyme discoverer Willy Burgdorfer breaks silence on
heated controversy
Posted: 09 Jun 2009 09:17 AM PDT
On February 28, 2007, the UNDER OUR SKIN film crew interviewed Willy Burgdorfer, Ph.D., M.D., and Scientist Emeritus at the
National Institutes of Health (NIH), for three hours at his home in Hamilton , Montana . Dr. Burgdorfer
is the discoverer and namesake of the spirochete (a type of bacterium) that
causes Lyme disease, called Borrelia burgdorferi. He has received numerous awards, including the
Robert Koch Gold Medal, the IDSA Bristol Award, the Schaudinn-Hoffman
Plaque, and the Walter Reed Medal. He is a coeditor of the book, “Aspects of
Lyme Borreliosis,” and has published over 220
research papers.
Just as we began filming, there was a pounding on the door, and we found
ourselves facing someone who turned out to be a top researcher at the nearby
Rocky Mountain Laboratories, a biolevel-4 NIH research facility. Standing on
the porch, our uninvited guest said, “I’ve been told that I need to supervise
this interview. This comes from the highest levels. There are things that Willy
can’t talk about.”
We were stunned. After all, Dr. Burgdorfer had been
retired from the lab since 1986. We were there to talk to a private citizen,
about the history of a very public discovery that had put him on the short list
for a Nobel Prize. Earlier that year, the NIH had refused our requests to
interview any of their Lyme researchers. What was going on? Why would the NIH
want to censor information about the fastest growing bug-borne disease in the
United States?
Fortunately, our iron-willed film director, Andy Abrahams Wilson, turned the
NIH handler away, and what followed was an amazingly candid interview about
Lyme disease—its dangers and its controversies. Here are highlights from this
three-hour interview:
Andy Wilson: Could you describe the “Aha!” moment when you discovered the
spirochete that causes Lyme disease?
Dr. Burgdorfer: I remember that time quite well.
Allen Steere called me in the summer of 1977 and
said, “Willy, I would like to discuss with you the methods you are using in
dissecting ticks, and [looking] for microbial agents.” I sat with him about two
hours that summer and told him over the phone how to dissect ticks. Then about
two months later he called again, and I repeated, again, the same thing. And he
finally said [in 1981], “Well, I’m willing to send you some serum [samples]. I
want you to examine them for me.”
But it was not an “Aha” [moment]. It was a “What in the hell? What’s in that
smear?” And then my work [on relapsing fever] as a Swiss student came back. [I
said to myself], “Willy, these are spirochetes!” The slide showed long slender
forms, a little bit curved, and they were only in the mid-part of the tick. Nowhere else. There were so many people who said, “That is
impossible Willie. You can’t get spirochetes out of hard-bodied ticks.” [But
from my work on] relapsing fever ticks from Africa , I
knew what a spirochete looked like. The Belgian Congo and Kenya are hotspots
for relapsing fever. Even Livingston [the African explorer and Scottish
missionary] was exposed, and he called it “tick fever.”
Andy Wilson: And what did they call this spirochete?
Dr. Burgdorfer: I discovered the agent producing Lyme
disease, so they called it Borrelia burgdorferi, after my name, Willy Burgdorfer.
The initial findings were published right away in Science magazine. And even
today, [this discovery] is considered a breakthrough in spirochetal
research. There are many laboratories that are using our techniques, applying
them to syphilis, because of similarities.
Andy Wilson: What are the similarities between Borrelia
burgdorferi and syphilis?
Dr. Burgdorfer: The similarities that I know of are
associated with the infection of the brain, the nervous system. The syphilis
spirochete, Treponema pallidum
has an affinity for nerve tissues. The Borrelia burgdorferi spirochete very likely has that too. Children
are especially sensitive to Borrelia burgdorferi.
The Lyme disease spirochete is far more virulent than syphilis. We don’t know
the end yet. And [we] can’t even make a [blood] smear with Borrelia
burgdorferi and see the organism. It’s there. But you
don’t see it. You cannot find this spirochete. Why not? After all, I have a
sick person here. He is trembling all over. His spinal fluid is full of
spirochetes. But when it comes to blood, it’s not there. So there is something
associated with this organism that makes it different.
Andy Wilson: Why is Borrelia burgdorferi
so hard to find in the body and culture outside the body?
Dr. Burgdorfer: Borrelia burgdorferi in the tissues of a patient is extremely
difficult to demonstrate, because, first of all, you don’t like somebody to
take samples out of your brain [to look] for spirochetes. The
same with other tissues. Every system in your body can be infected with
spirochete. But to prove that is extremely difficult. It demands surgical work,
which is very expensive
Andy Wilson: Are you a believer in the idea of persistent Lyme infections?
Dr. Burgdorfer: I am a believer in persistent
infections because people suffering with Lyme disease, ten or fifteen or twenty
years later, get sick [again]. Because it appears that this organism has the
ability to be sequestered in tissues and [it] is possible that it could
reappear, bringing back the clinical manifestations it caused in the first
place. These are controversial issues for microbiologists, as well as the
physicians who are asked to treat patients.
Andy Wilson: How do you feel about the controversy in the Lyme world?
Dr. Burgdorfer: The controversy in Lyme disease
research is a shameful affair. And I say that because the whole thing is
politically tainted. Money goes to people who have, for the past 30 years,
produced the same thing—nothing. Serology has to be started from scratch with
people who don’t know beforehand the results of their research.
There are lots of physicians around who wouldn’t touch a Lyme disease patient.
They tell the nurse, “You tell the guy to get out of here. I don’t want to see
him.” That is shameful. So [this] shame includes physicians who don’t even have
the courage to tell a patient, “You have Lyme disease and I don’t know anything
about it.”
Andy Wilson: What about the Lyme vaccine?
Dr. Burgdorfer: The [first generation] vaccine was
not specific enough and not strong enough. So what is needed is additional work
on a vaccine. What we have right now is a good example of work that goes to
industry [too soon], and industry says, “Okay fine, get it out. “ And somebody
says, well it’s too early. And it’s already on the market … and you see that
every day …You see that this company is falling down, and these guys are
realizing that the vaccine work is full of holes and never should have come
out. A lot of people are going to pay for that. They’re going to get sick with
Lyme as a result of the vaccination. Then you’re in trouble.
Andy Wilson: What do you think about the relationship between Lyme and
neurodegenerative disease like Alzheimer’s and Parkinson’s disease?
Dr. Burgdorfer: Right now they are building a
research center at Columbia University, to study this possibility, because many
physicians believe that neurologic manifestations, regardless [of] what type,
are typical for Lyme disease.
Andy Wilson: What do you most regret about what has happened, in the aftermath
of your discovery?
Dr. Burgdorfer: I most regret that the technology
used to diagnose and to even treat Lyme disease wasn’t worked all the way
through. It [was based on] only a few results, then published. And later on,
people [wanted] to take them back. I think Borrelia burgdorferi is too serious an [infectious] agent to play
with, and with many laboratories, the severity of the disease is overlooked.
Andy Wilson: What’s the next stage of research?
Dr. Burgdorfer: Neurologic manifestations have to be
the next stage of research. Also [Borrelia
burgdorferi’s] antigenicity.
Ecologically, the diversification of Borrelia is
tremendous. Because of the spirochete’s ability to change—to change its physiology,
to change its “antigenic” structure for instance—a spirochete may be capable of
producing disease or not.
And one piece of work that needs to be done, that has lately been neglected, is
development of the spirochete—whether it transfers [genes via] fission, or
whether individual spirochetes have the ability to break into spheres or
particles. We don’t know yet how they do it but they do. They go into the
lymphocytes, they go into every tissue. Just because we have not seen [them],
does not mean that they are not there. Once the immune response is down, are
[they] capable of re-entering the bloodstream and producing disease?
Andy Wilson: Do you have Lyme?
Dr. Burgdorfer: No. I don’t. But I say that
cautiously. Because I have been working with Lyme disease
ever since 1981.
_______
Soon after we turned-off the camera and began packing
up our gear, Dr. Burgdorfer told us with a sly smile,
“I didn’t tell you everything.”
Source: http://lymesentinel.blogspot.com/search/label/Biowarfare